Coronavirus: Side effects from COVID-19 booster shots more common than from regular doses, study says

 While COVID-19 vaccines can protect people from severe illness and death, the protection begins to wane after initial vaccine doses, making booster shots necessary for maintaining immunity.

However, it is also known to have some symptom-like side effects - mostly ranging from minor to moderate. Some people have side effects from the vaccine, which are normal signs that their body is building protection. These side effects may affect their ability to do daily activities, but they should go away in a few days. Some people have no side effects, and allergic reactions are rare. Researchers report that side effects appear to be stronger from COVID-19 boosters than from initial doses of the vaccine, according to a new study published in JAMA Network Open.

This cohort study was conducted using electronic health record (EHR) data from December 2020 to October 2021 from the multistate Mayo Clinic Enterprise. Participants included 47 999 individuals who had received 3-dose COVID-19 mRNA vaccines. Data were analyzed from September through November 2021. Significantly increased reporting was found for low-severity adverse events such as fatigue, lymphadenopathy, nausea, and headache.